A Knife to the Heart

The history of transplant surgery.

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Latest Episodes

  • Season 1 Episode 4: Against Nature

    Account of how American, British and French surgeons overcame medical and ethical obstacles to perform the first successful organ transplant in 1954. Among those appearing are Richard Herrick, whose donated kidney saved the life of his identical twin, and Nobel prize-winner Joseph Murray, who carried out the operation. Also British surgeon Sir Roy Calne describes how he helped devise a way of overcoming one of the most serious problems facing pioneers in the field : organ rejection

  • Season 1 Episode 3: Walking the Tightrope

    The penultimate programme in the series focuses on transplant rejection, caused by the body's natural tendency to destroy foreign tissue. Medications to counter the problem can have devastating side-effects and the search for improved drugs has had its fair share of setbacks : one high-flying medical researcher even faked evidence allowing him to claim he'd found the perfect solution

  • Season 1 Episode 2: The Great Organ Hunt

    Attempts to meet the demand for transplantable organs, including controversial attempts to genetically engineer pigs to provide suitable viscera